We used WD40 domains from the yeast -COPI and -COPI subunits, which have been used extensively in prior structural investigations 43,61,62
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However, the intended dose escalation of CAR T cells was hindered by on-target toxicity, which cause cystitis
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The skin tissues from the back of mice were removed and weighed, according to 0.1 g of tissue, 1 ml of reagent I in liquid nitrogen and grind