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Infliximab maintains a high degree of clinical response in patients with active psoriatic arthritis through 1 year of treatment: results from the IMPACT 2 trial

The active caspase-1 converts pro-IL-18 and pro-IL-1 into IL-18 and IL-1, which further induces an inflammatory response and triggers pyroptosis [74, 88]

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Although both semaglutide and cagrilintide induce satiety, they exert their effects in different regions of the brain, suggesting a synergistic effect on appetite regulation, warranting the investigation of these drugs as a combination therapy