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Because these two sets of data were generated at different times, they were treated as independent cohorts for analysis

51 Alignment with this concept, Liang et al 52 considered that elevated TMAO in AF patients could guide antithrombotic therapy for patients with low and intermediate risk of embolism

Chen LY, Zhang YD & Zhu FY

Ferroptosis Ferroptosis is a recently discovered programmed cell death modality associated with intracellular iron overload that is distinct from apoptosis

By inhibiting NNMT, 5-Amino-1MQ increases cellular SAM and NAD+ levels, enhances NAD+ salvage pathway flux, activates SIRT-1, boosts oxidative phosphorylation (OXPHOS), and influences cellular energy homeostasis and epigenetic modifications

Luger TA, et al