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Napier et al., 1995

Glutathione Is Essential in a Broad Range of Metabolic Processes Glutathione acts to neutralize a toxic metabolic byproduct: Methylglyoxal Glutathione is involved in the protein disulfide bond rearrangement that is necessary for the synthesis of one-third of the bodys proteins It protects the body from the oxidative damage caused by glutathione peroxidase by acting as a helper molecule for certain enzymes The liver uses Glutathione to help detoxify fats before the gallbladder emits bile, supporting healthy digestion Detoxification: Glutathione may also be crucial in the removal and detoxification of carcinogens, and according to recent studies, alterations in this metabolic pathway can influence cell survival profoundly

Funnel plots were used in analysis with 10 studies for heterogeneity followed by sub-analysis to locate the source of heterogeneity ( Table 5 )

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Liraglutide (brand name Saxenda) is an older GLP-1 medication that requires daily injections rather than weekly