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Glycemic Control in Type 2 Diabetes In people with type 2 diabetes , retatrutide has produced HbA1c reductions close to 2 percentage points in trials, a magnitude often associated with multi-drug regimens

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(2025) 45:e16150

(Source: AJMC, July 2026) Which Symptoms Actually Drive Discontinuation In longer-term trials that broke out individual adverse event categories, nausea was the leading cause of discontinuation , followed by vomiting and diarrhoea