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A 2023 meta-analysis in Fertility and Sterility (N=522 across 11 RCTs) found that GLP-1 agonists reduced BMI by a weighted mean of 4.2 kg/m and improved menstrual regularity in 60% of women with PCOS at 24 weeks

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Last week, the product information for all GLP-1 and dual GLP-1/GIP receptor agonists was also updated to highlight the risk of severe acute pancreatitis, including rare reports of necrotising and fatal pancreatitis

Most patients run 612 months of active loss, then a maintenance phase

lipotropic compounds assist liver detoxification and fat breakdown processes