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Covalent attachment of P15 peptide to titanium surfaces enhances cell attachment, spreading, and osteogenic gene expression

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As a mitochondrial-derived peptide, it behaves as a signaling molecule that communicates metabolic information from your mitochondria to the rest of your body

doi: 10.1038/sj.bjp.0704467

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5 For example, recent preclinical and clinical observations highlight the role of gut-derived peptides such as GIP, GLP-2, and to a lesser extent, GLP-1 in the maintenance of overall skeletal health ( Figure 2 ), 6,7,8 opening new avenues for the understanding and potential treatment of bone disorders