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Persistent and excessive alcohol consumption promotes the microsomal ethanol oxidation system rather than the dehydrogenase pathway

and increased levels of TGF- compared to healthy individuals

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Mirmasoumi G, Fazilati M, Foroozanfard F, Vahedpoor Z, Mahmoodi S, Taghizadeh M, et al

The Main Benefit: Bypassing the Stomach For B12 to absorb, it must follow a complex pathway that requires the normal function of the stomach, pancreas, small intestine, and their acids and enzymes

Chronic pharmacological potentiation of this pathway could theoretically promote tumor development or progression in individuals with pre-existing pre-malignant cells