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However, other randomized controlled trials have not found any benefit of citicoline treatment in the management of acute ischemic stroke (98, 99), including a recent trial evaluating its effects when provided immediately following endovascular thrombectomy (i.e., recanalization therapy) and continued for 42 days (100)

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150 mg/kg D-luciferin (#ST196, Beyotime) was intraperitoneally injected to mice