By formulating with methylated vitamins, Grns ensures every body can utilize and experience the full benefits, including those with the MTHFR gene
But in such a new field of research, customers of these weight-loss startups are essentially test subjects, says Chastain: The danger to consumers is that they take on risk and expensive medication based on a claim that is not scientifically basedthats not evidence-based. Startups, by nature, exist to fix problems
Think of it as a next-generation version of drugs like Ozempic (which hits one receptor) and Zepbound (which hits two)
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Last reviewed: May 18, 2026 Last updated: May 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Hepatic histopathology (Fig.4-A, B) showed that both semaglutide and tirzepatide significantly reduced the non-alcoholic fatty liver disease activity score (NAS) by decreasing steatosis and cell ballooning, compared to the non-restricted diet model group