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Fatigue is listed as a reported adverse reaction for some GLP-1 receptor agonists, particularly those used at higher doses for weight management such as semaglutide (Wegovy) and liraglutide (Saxenda)

Ageing causes a decline in the production of cell energy

Additionally, it can provide an energy boost and reduce fatigue, which can be beneficial during a weight loss journey

2025 Rosa Castellano, Marie-Hlne Perruchot, Sophie Tesseraud, Sonia Mtayer-Coustard, Elizabeth Baeza, Yves Mercier, Florence Gondret

10.3390/toxics10110665 38 HuF.GuoQ.WeiM.HuangZ.ShiL.ShengY.et al (2020)

Sedentarism in CKD increases cardiovascular and cognitive risks, whereas physical activity improves brain health by boosting blood flow, neuroplasticity and reducing inflammation