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Mitotracker labeling showed an increased mitochondrial DNA quantity, enhanced cellular aerobic respiration, citrate synthase and cytochrome c oxidase activities when the cells were exposed to small concentrations (1030 m) of PQQ for 2448 h (Chowanadisai et al., 2009, 2010)

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Perley and D.M

Thus, the ascorbic acid- induced spectral change is likely to result from oxidation and breakdown of the porphyrin ring