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using treatment effects evaluated by the treatment policy estimand (reflecting the intention-to-treat population) in PIONEER 4 for both arms
More clinical research and experiments in terms on antioxidant therapy, especially in deciding optimal drug dosages and treatment efficacy, stay pivotal for future investigations ( Above all, this review thoroughly summarizes the function of oxidative stress in periodontitis and discusses how antioxidants, by inhibiting oxidative stress, are applied in its treatment