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High dose oral cobalamin may be a suitable alternative in selective cases, where intramuscular injections are not tolerated and compliance is not a problem

In addition to human breast tumors, IFP increases in experimental models of breast cancer, such as severe combined immunodeficient mice bearing highly invasive, triple-negative MDA-MB-231 human breast cancer tumors [20] and BN472 rat mammary carcinomas [21]

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New England Journal of Medicine, 385(6), 503-515