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A major potential advantage of the peptide is that due to its apparent GHRH receptor specificity, it may not induce any significant change in the levels of other endocrine markers such as prolactin, insulin, cortisol, glucose, or thyroid hormones

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Kim K, et al

Since it was manufactured as a drug for diabetes patients, it primarily works to increase the level of insulin that your body produces

For detailed guidance on how quickly semaglutide starts working , check our timeline guide

Semaglutide/Tirzepatide/Retatrutide can increase your heart rate while you are at rest