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The double-stranded DNA homology-directed repair (HDR) template (HiBiTBRD4 with extensions, shown below), the RNP complex and an electroporation enhancer (Integrated DNA Technologies) were then electroporated into Jurkat cells using an Amaxa 4D-Nucleofector (Lonza)

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Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis