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It dissolves more poorly in water the colder the water is, and its susceptible to significant degradation depending on the temperature and pH of its solution and the time it spends there.17 Other forms of creatine have come out that try to account for this, including buffered forms that alter its pH to make it dissolve more thoroughly in cold water

Ciacci C, Peluso G, Iannoni E, Siniscalchi M, Iovino P, Rispo A, Tortora R, Bucci C, Zingone F, Margarucci S, Calvani M

And if you feel that the initial consultation process is lacking the kind of substance that you typically associate with consultations as a new patient, we'd suggest you consider that a sign that you should seek additional medical advice elsewhere before proceeding

You are not alone

H., Winkler M

Endocrinology 147, 55575563