All information presented is intended solely to support qualified researchers, laboratories, and institutions in the study of peptide compounds under appropriate research conditions
Glutathione can be found in an oxidized form and a reduced form, but the reduced form is the only one that has antioxidant activity
This integration of removal and regeneration processes reflects the evolutionary optimization of antioxidant capacity to preserve cellular homeostasis under fluctuating environmental conditions
*Correspondence: Yan Sun [email protected] Deng [email protected] These authors have contributed equally to this work Present address: Shuai Huang, Yuying Sun, Xinxin Yu, Xuan Ren, Lei Wang, Yan Sun, and Aijun Deng, School of Clinical Medicine, Shandong Second Medical University, Weifang, China Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Artesunate may inhibit the proliferation of lung cancer cells, downregulate the expression of anti-apoptotic molecules Bcl-2 and survivin, upregulate the expression of pro-apoptotic molecules P53 and Bax, and increase the activity of caspases and apoptosis rate through the PPAR-/TGF-1/Smad2/3, AKT/Survivin, P38/JNK/ERK, and MAPK pathways (Pan et al., 2021
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