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10.1016/S0140-6736(20)30251-8 105

Extension of the native insulin-like growth factor-1 sequence by 13 amino acids and substitution of glutamic acid-3 with arginine produced a structurally distinct analogue central to IGF-1 receptor signalling studies

(Review) Comprehensive review showing -MSH exerts broad anti-inflammatory effects (NF-B, cytokines, adhesion molecules), and highlights KPV as a non-pigmenting C-terminal tripeptide with therapeutic potential for skin and bowel inflammation and other immune-mediated conditions.

Being a natural component of the skin, it is well tolerated by all skin types, including those with acne-prone and sensitive skin

The gut microbiota and diabetes: research, translation, and clinical Applications-2023 diabetes, diabetes care, and diabetologia expert forum

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