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[197] demonstrated that polystyrene NPs functionalized by amine groups (PS-NH2) efficiently interact with cell membranes compared to PS-COOH (negatively charged particles)

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In addition to serum cholesterol abnormalities, the upregulation of cholesterol-related genes has also been observed in several types of cancers, including sarcomas, acute myeloid leukemias, melanomas, and breast cancers (Cai et al., 2016