DIC 8(4):119 Wilding JPH, Batterham RL, Davies M, Van Gaal LF, Kandler K, Konakli K et al (2022) Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension
Importance of Consistent Temperature Even when within +2 C to +8 C, fluctuations can damage GLP-1 drugs
Side effect management during titration Several strategies can reduce GI side effects without altering the dosing schedule
Try sauerkraut, kimchi, tempeh, and even sourdough bread
Effectiveness and Side Effects: Tirzepatide is a dual receptor agonist, which is why it is a potentially more potent treatment, but its use may also be associated with more side effects compared to liraglutide
GLP-1 receptor : Agonism at the GLP-1 receptor provides appetite suppression through central hypothalamic and brainstem signaling, delays gastric emptying, and enhances glucose-dependent insulin secretion