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HCV infection can induce ROS-mediated oxidative stress, leading to the formation of 8-hydroxydeoxyguanosine (8-OHdG), which is an indicator of oxidative DNA damage 83

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In contrast to the above studies, Straub et al., observed a suppression of inflammation and immune cell activation after performing transcriptomic analysis of abdominal and thigh subcutaneous adipose tissue of 14 lipedema patients ranging from stages 13 (Straub et al., 2025)