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Combinative treatment of -elemene and cetuximab could induce ferroptosis of KRAS-mutant colorectal cancer cells (CRC) by iron-dependent ROS accumulation, GSH depletion, lipid peroxidation, upregulation of HO-1 and transferrin, and downregulation of negative regulatory proteins for ferroptosis (GPX4, SLC7A11, FTH1, glutaminase, and SLC40A1), thus inhibiting tumor growth and lymph node metastases in vivo ( Curcuma zedoaria [Zingiberaceae
doi:10.1016/j.physbeh.2018.01.006
These properties make Pinealon a valuable tool for aging research, providing insights into the cellular and molecular processes that determine longevity and offering potential strategies for maintaining cellular function throughout the aging process
doi: 10.1016/S0140-6736(18)32590-X
The crosstalk between these cells is a crucial link in the chain of events that transforms toxic exposures into neurological symptoms
There are two formulas one with zinc and one without
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