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How long can AOD-9604 be safely used based on clinical trial data

It's the distinction between a compound that works and one that doesn't

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However, no improvement in clinical assessment, tissue pathology, differences in vessel number, or laminin expression in the lesion was observed with chronic drug administration

In the current study, MTX caused a pronounced decline in the dielectric constant, dielectric loss and the conductivity of kidney tissue, which may be attributed to MTX-induced kidney tissue damage