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What is considered a high dosage of B12

One piece of research led by the Amsterdam Medical Centre concluded that the drug has low risk for severe adverse events. Guidance recommends users take the drug for two years at the moment, says Gately

The drugs are large protein molecules and thus very vulnerable to digestive enzymes and acid degradation

(also in this protein) Note that this protein also includes vitamin D3 , and that's not just to pretty up the label

8 The intracellular content of NADP(H) differs markedly among tissues and cell types