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Additionally, investigations using cellular models have verified astaxanthin's capacity to activate the Nrf2/ARE pathway and upregulate antioxidant enzymes, providing mechanistic insight into its protective effects against oxidative damage

doi: 10.3233/JAD-2005-7107

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Biomed Pharmacother 92:9981009 Funding No specific source of funding is associated with this work

Such genetic alterations were all reverted by low doses if IGF-1 replacement therapy for only 10 days

The most significant disparities emerged during the recovery phase after the first exercise challenge, where pathway analysis revealed significant changes in numerous metabolic pathways, including the urea cycle, and glutamate and pyruvate metabolism