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Hypotheses 86 , 39 (2016)

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An imbalance in glutathione metabolism, defined by lower GSH:GSSG, has been linked to a number of chronic diseases including feline chronic renal failure (Reference Keegan and Webb43) and in humans, cancer, neurodegenerative disorders, cystic fibrosis, viral infection, diabetes mellitus, renal failure and liver disease (Reference Wu, Fang and Yang44)