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The incidence was also calculated over the whole index period, 20192023

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Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic cells

GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the dual agonist tirzepatide are backed by STEP ( The New England Journal of Medicine , 2021), SURMOUNT (NEJM, 2022), and SURMOUNT-OSA (NEJM, 2024)

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