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Your practitioner will advise on the most appropriate course of treatment following consultation

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Quality verification becomes even more important when combining compounds, since impurities or inaccurate dosing in one product amplify risks when another compound is added to the protocol

They were then mixed with 1 mL of a 40:40:20 methanol: acetonitrile: water solution precooled to 20 C, followed by vortexing for 5 min, incubation at 20 C for 10 min, and centrifugation at 4 C and 12,000 g for 15 min