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Trends Neurosci 36:305312 Frei R, Akdis M, OMahony L (2015) Prebiotics, probiotics, synbiotics, and the immune system: experimental data and clinical evidence

2013 Sep-Oct;39(5):514-21

Some studies suggest that 10 to 20% of patients continue experiencing symptoms beyond one year despite conservative treatment

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Clinical experience targeting T2DM has shown that the 3 mg dose is more effective than the 1.8 mg dose in managing T2DM in combination with other hypoglycemic drugs and improving weight