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Dihexa binds to HGF with extraordinary affinity (Figure 43), blocking HGF dimerization (Figure 44), and markedly augments the ability of HGF to signal to c-Met ( Figure 45) and initiate cellular responses (as discussed above)

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Larsen, A., Mohamed, K., Sonne, N., Bredtoft, E., Andersen, F., Karsdal, M., & Henriksen, K