Type 2 diabetes in adults: management NG28
In animal experiments, particularly in mouse models, GDF-15 enhances satiety and reduces food intake through its action on the central nervous system
Ligand-specific factors influencing glp-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells
Non-semaglutide GLP-1 medications from Henry Meds Henry offers two other GLP-1 RAs in addition to semaglutide: Tirzepatide: the active ingredient in Mounjaro and Zepbound Liraglutide: the active ingredient in Saxenda and Victoza Of the three drugs, tirzepatide has shown the highest weight loss rates in studies, with one study showing nearly 18% of body weight lost after 72 weeks
Common side effects of weight loss medications Many people who experience the most common side effects from weight loss medications say they resolve after their bodies adjust to the new medications, while others have side effects that persist
Eli Lillys Phase 3 TRIUMPH-4 trial (December 2025) reported that participants taking 12mg of Retatrutide over 68 weeks lost an average of 28.7% of their body weight, the highest result ever reported at that stage for any obesity-related compound
