it reports previously unpublished work
WHO ITS IDEAL FOR
ALS can be phenotypically classified into either limb onset (LO) cases with upper and lower motor neurons being affected, accounting for 70% of the cases, or Bulbar onset (25%) in which speech and swallowing issues first arise that are followed by later stage limb weakness (Zarei et al., 2015)
Hypothyroidism is classified as primary or secondary, with primary causes including iodine deficiency, autoimmune diseases (e.g., Hashimotos thyroiditis), enzymatic damage, radiotherapy, thyroid surgery, certain medications, and chronic or infiltrative conditions, while secondary hypothyroidism results from pituitary or hypothalamic disorders
Understanding the mechanism of how increases in TMAO promotes CVDs will potentially facilitate the identification and development of targeted therapy for CVDs
Park et al., 2013)