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373,374,375 The transport of calcium ions across mitochondria is mediated by the mitochondrial calcium uptake family member protein (MICU)

Journal of Cosmetic Science , 60(4), 377385

Yu M, Tomasa G

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Researchers must justify TB-500 use under the 3Rs framework (replacement, reduction, refinement) and demonstrate that scientific objectives cannot be achieved through non-animal methods

To avoid this, niacin can be taken with baby aspirin, with food, or with an extended-release form of niacin/nicotinic acid (one in which the niacin is mixed with an edible wax such as carnauba wax)