One further nuance worth noting: the addition of GIP in both tirzepatide and retatrutide is hypothesised to improve gastrointestinal tolerability relative to GLP-1 alone at comparable efficacy
S.Al-HouraniK.EddlestonM.BatemanD
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D., Sousa, M
doi: 10.1136/bmjnph-2020-000085 31 CallawayE.LedfordH
The thought of how incredibly inaccurate this equation and number is, and the possible implications it can have in people who have eating disorders, body dysmorphia, anxiety, or basically any sort of problematic relationship with their bodies, is really, really disturbing