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You can read the abstract of this article at Type 2 diabetes is a multifaceted condition characterized by impaired insulin secretion, heightened glucagon secretion, and exacerbated insulin resistance, often linked to obesity

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Abstract The pathological condition known as ischemia reperfusion injury (IRI) is characterized by an initial restriction in the amount of blood supply followed by reperfusion which paradoxically aggravates irreversible neuronal damage and cell death