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The initial step in the MD workup was examination for mtDNA gene abnormalities by either a targeted analysis for common mutations and/or deletions and/or sequencing of the entire mtDNA genome (Baylor Medical Genetics Laboratory, Houston, TX, USA)

10.1016/j.ygcen.2010.07.014 19 Christ-CrainM.MeierC.PuderJ.StaubJ