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NOAEL, No Observed Adverse Effect Level

Additionally, the study explored the effects of these regimens on cognition and depression

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Boulware SD, Tamborlane WV, Rennert NJ, Gesundheit N, Sherwin RS

In this regard, the balance of neurotransmitters in the brain, specifically norepinephrine (NE), dopamine (DA), and serotonin (5-HT), is a major determinant of the overall weight loss properties of most appetite suppressants [14, 25, 64]