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That definitional chaos has consequences: it delays real diagnoses, produces nocebo effects with measurable physiological outcomes, and leads athletes to reduce training they didn't need to reduce

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Onset: Localized respiratory effects are often noticed within the session

In a recent study that included 48 patients 19 were treated with 50 mg/day pyridoxine hydrochloride and 22 with placebo, no statistically significant differences were found between the two groups (72)

While a mixed-model approach may be considered for retaining related individuals while controlling for relatedness, the analytic framework of our study required the removal of closely related samples to ensure independence of observations