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Yes, when administered under medical supervision, it is generally safe for all skin types

Resveratrol protects against methotrexate-induced hepatic injury in rats

CoQ10 supplementation (400-600 mg/day) becomes more relevant, and so does making sure your vitamin D levels are adequate

Atkuri, K

Biochemistry 38 , 32113217 (1999)

In addition, pro-inflammatory cytokines can act to steal tryptophan away from serotonin and melatonin pathways (via up-regulation of the enzymes IDO and TDO), increasing the activity of the NMDA agonist quinolinic acid, and further antagonising stimulation of NMDA pathways, which subsequently exacerbates mood and sleep issues