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Furthermore, insulin resistance and hyperinsulinemia can lead to goiter, proliferation of thyroid tissues, and an increased incidence of nodular thyroid disease (6)
The medication is not recommended during second and third trimesters of pregnancy
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Tirzepatide (Mounjaro and Zepbound) at the 15 mg dose showed comparable lean-mass loss in pattern but modestly less in proportion (approximately 25% of total weight loss as lean mass