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Melanotan is a synthetic peptide a short chain of amino acids

When soluble fiber reaches the large intestine undigested, gut bacteria ferment it into short-chain fatty acids, primarily butyrate, propionate, and acetate

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Activation of FXR stabilizes the nuclear co-repressor (NcoR) at the NF-B response element on the IL-1 promoter, while decreasing the expression of TNF-, IL-1, IL-2, IL-6 and IFN- mRNA, thereby reducing the extent of inflammation (Vavassori et al., 2009)

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Pancreatic steatosis and metabolic pancreatic disease: a new entity