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Building on the success of GLP-1 agonists like Semaglutide introduces a dual mechanism of action by combining the GLP-1 agonist with a GIP (Glucose-dependent Insulinotropic Polypeptide) agonist

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However, removal of the first 6 amino acids yields shorter compounds (737 and 736) that have enhanced biological activity [14]

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Considered to be one of the most important advances in the management of obesity and metabolic disorders , tirzepatide offers a comprehensive approach for the treatment of long-term weight control