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Ethics statement The animal study was reviewed and approved by the ethics committee of China Medical Universitry

The serious warnings matter

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The change rates of Body Mass index (BMI) from baseline values were used as an evaluation indicator

There are also the side effects like nausea, vomiting and constipation associated with the buildup of food and waste in the digestive tract

These approaches are aimed at extending their pharmacological half-lives and attaining supraphysiological stimulation of GLP-1R