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Generalized tonicclonic seizures (GTCS) present a considerable risk for SUDEP, affecting not only the brain but also causing cardiogenic dysfunction characterized by excessive iron accumulation and cardiomyopathy (IOC), along with electrical and mechanical abnormalities referred to as epileptic heart, which carries a high likelihood of malignant bradycardia (67)

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doi:10.1111/obr.12839 5

administration, TAT-DAT NT , at the dose of 40 nmol ( i.c.v

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