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There is no clinical evidence that any transdermal or cosmetic GLP-1 patch can meaningfully affect blood sugar, appetite, or weight

& Deacon, C

The large 2025 meta-analysis quantified this as approximately 63% higher gastrointestinal adverse event rates compared with placebo, and gallbladder disorders were about 26% higher

Retatrutide is an investigational once-weekly injectable medication

Fermented Foods for Gut Health While Taking GLP-1 Medications Fermented foods can support gut health, improve digestion, and help replenish beneficial bacteria while taking GLP-1 medications

Understanding this timeline is crucial in managing client expectations and providing supportive care