For the treatment groups with CuCl 2 and Cu(OAc) 2 , copper compounds had a positive correlation with the protein level regulated
Although a possible neurotransmitter role was claimed, i.e., for prostaglandins [144,145,146,147] and somatostatin [148,149,150], this was not combined with the cytoprotective effect and possible pleiotropic effect (organoprotection)
Recently, exhaustion of GSH in cisplatin-resistant cells has been extensively utilized to strengthen the cytotoxicity of cisplatin and sensitize chemotherapy ( Platinum precursors such as Pt () are applied to produce Pt () as a GSH-scavenging agent
Synergy with other actives Because GHK-Cu focuses on the scalps structural and inflammatory environment, it can complement proven treatments like minoxidil or supportive haircare routines rather than replacing them
2021 Dec;11(12):4045-4054
5 Limitation A key limitation of this review lies in the considerable heterogeneity among the included studies, particularly in the analysis of depressive symptoms