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High-quality human clinical trials are lacking, and optimal dosing, long-term safety, and efficacy have not been established, meaning its use for IBS and Crohns should be considered investigational rather than a standard therapeutic option

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Proper hydration supports healthier skin, improves overall skin appearance, and may help the body respond better to supplements

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Puissant-Lubrano B, Apoil PA, Guedj K, Congy-Jolivet N, Roubinet F, Guyonnet S, et al

However, advanced research is exploring encapsulation methods like liposomes or conjugation with larger molecules (PEGylation) to protect GHK-Cu from enzymes