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Newer weight loss medications called glucagon-like-peptide-1 receptor agonists (GLP-1s), such as Zepbound or Wegovy , may promote more significant weight loss results

Direct injection of GLP-1 into the basal ganglia can increase the release of the neurotransmitter glutamate from neurons, demonstrating that synaptic transmitter vesicle release can be enhanced by GLP-1 (Oka et al., 1999b)