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A structural overlay of the ipratropium-bound structure and the occluded structure demonstrates that ipratropium in principle could fit within the occluded substrate-binding site cavity (Supplementary Fig
Its bioavailability is somewhat improved over that of ordinary GSH, but remains limited
In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse
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